Nasiru Shua’ibu, a professor in the Biochemical Parasitology
Department of Ahmadu Bello University (ABU), Zaria, has developed a new
malaria vaccine to prevent high rate of death from malaria fever.
Speaking with the News Agency of Nigeria (NAN) in Zaria, Kaduna State
on Tuesday, Mr. Shu’aibu said the new malaria vaccine was different
from others currently in use.
Mr. Shu’aibu, who is currently working with the Institute of Tropical
Medicine, Japan, said the result of the research on the new vaccine
would soon be out for Nigerians to use.
“In a simple term that a layman can understand, the content of this
malaria vaccine research is difficult, but let me try if I could
simplify it, it is called DNA Vaccine.
“It is a new technology for discovery and delivery of vaccine against
any infectious disease that was developed in the early to mid 1990s.
“The DNA of the malaria parasite was extracted and the portion of the
DNA that is tested to be a good vaccine candidate is subjected to
molecular biology methods which are used to produce a lot of the DNA,”
Mr. Shu’aibu said.
According to him, the amount of DNA from the malaria parasite was
very minute in quantity and to expand the quantity, Polymerase Chain
Reaction (PCR) was used.
“Then a method of cloning is now used to insert the DNA into a vehicle that will carry the DNA into either animal or human body.
“It
is then injected into the body of the animal or human and it eventually
enters the cells of the animal in the same way a virus enters and
infects cells.
“The injected DNA now uses the cells in the body to produce chemicals
that will prevent malaria from infecting the body,” Mr. Shu’aibu said.
He said the vaccine was different from any of the licensed vaccines like polio and other EPI vaccines.
Mr. Shu’aibu added that the approach was also different from the
other malaria vaccine (RTS,S/AS01) that was likely to be licensed but
the goals were the same, to control and eventually eliminate malaria.
Nigeria, with an estimated population of over 170 million, constitutes the highest malaria burden in Africa and in the world.
Mr. Shu’aibu doubted the figures from the National Malaria Control
Programme (NMCP) indicating progress in containing the disease.
“I still doubt; the tools currently used to fight malaria are not
sufficient to have a substantial and sustained impact that is needed to
resolve the malaria crisis in Nigeria,” he said.
Mr. Shu’aibu said the need to monitor the growing resistance to anti-malarial drugs and insecticides.
He said if not checked and documented, it would jeopardise years of
global public health success and investments in malaria control.
(NAN)
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